| 09 Oct 2021 Hallam Grange B vs. Buxton A (away: W L Saturday Div 3 2021) |
| 16 Oct 2021 Buxton B vs. Rustlings A (home: W L Saturday Div 5 2021) |
| 16 Oct 2021 Graves B vs. Buxton A (away: W L Saturday Div 3 2021) |
| 23 Oct 2021 Buxton B vs. Stocksbridge C (home: W L Saturday Div 5 2021) |
| 23 Oct 2021 Stocksbridge B vs. Buxton A (away: W L Saturday Div 3 2021) |
| 30 Oct 2021 Buxton A vs. Hallamshire B (home: W L Saturday Div 3 2021) |
| 30 Oct 2021 Graves C vs. Buxton B (away: W L Saturday Div 5 2021) |
| 06 Nov 2021 Buxton A vs. Bamford A (home: W L Saturday Div 3 2021) |
| 13 Nov 2021 Buxton A vs. Doncaster B (home: W L Saturday Div 3 2021) |
| 13 Nov 2021 Hallamshire C vs. Buxton B (away: W L Saturday Div 5 2021) |
| 20 Nov 2021 Buxton A vs. Barnsley B (home: W L Saturday Div 3 2021) |
| 20 Nov 2021 Chesterfield B vs. Buxton B (away: W L Saturday Div 5 2021) |
| 27 Nov 2021 Buxton A vs. Hallam Grange B (home: W L Saturday Div 3 2021) |
| 04 Dec 2021 Buxton A vs. Graves B (home: W L Saturday Div 3 2021) |
| 04 Dec 2021 Abbeydale vs. Buxton B (away: W L Saturday Div 5 2021) |
| 11 Dec 2021 Buxton A vs. Stocksbridge B (home: W L Saturday Div 3 2021) |
| 18 Dec 2021 Buxton B vs. Bamford B (home: W L Saturday Div 5 2021) |
| 18 Dec 2021 Hallamshire B vs. Buxton A (away: W L Saturday Div 3 2021) |
| 08 Jan 2022 Mexborough B vs. Buxton B (away: W L Saturday Div 5 2021) |
| 08 Jan 2022 Bamford A vs. Buxton A (away: W L Saturday Div 3 2021) |
| 15 Jan 2022 Buxton B vs. Rustlings B (home: W L Saturday Div 5 2021) |
| 15 Jan 2022 Doncaster B vs. Buxton A (away: W L Saturday Div 3 2021) |
| 22 Jan 2022 Buxton B vs. Grove B (home: W L Saturday Div 5 2021) |
| 22 Jan 2022 Barnsley B vs. Buxton A (away: W L Saturday Div 3 2021) |
