| 13 May 2021 Buxton vs. Chesterfield B (home: Ladies' Division 3 2021) |
| 15 May 2021 Barnsley C vs. Buxton (away: Men's Division 4 2021) |
| 18 May 2021 Barnsley B vs. Buxton (away: Midweek Mixed Div 4 2021) |
| 20 May 2021 Buxton vs. Brentwood B (home: Ladies' Division 3 2021) |
| 22 May 2021 Buxton vs. Moorgate B (home: Men's Division 4 2021) |
| 25 May 2021 Brentwood B vs. Buxton (away: Midweek Mixed Div 4 2021) |
| 27 May 2021 Buxton vs. Doncaster B (home: Ladies' Division 3 2021) |
| 29 May 2021 Stocksbridge B vs. Buxton (away: Men's Division 4 2021) |
| 01 June 2021 Buxton vs. Rustlings A (home: Midweek Mixed Div 4 2021) |
| 03 June 2021 Buxton vs. Stocksbridge A (home: Ladies' Division 3 2021) |
| 05 June 2021 Buxton vs. Graves C (home: Men's Division 4 2021) |
| 08 June 2021 Hallam Grange vs Buxton (away) |
| 10 June 2021 Grove B vs. Buxton (away: Ladies' Division 3 2021) |
| 12 June 2021 Buxton vs. Bradfield (home: Men's Division 4 2021) |
| 15 June 2021 Thorncliffe B vs. Buxton (away: Midweek Mixed Div 4 2021) |
| 17 June 2021 Beauchief C vs. Buxton (away: Ladies' Division 3 2021) |
| 19 June 2021 Welbeck B vs. Buxton (away: Men's Division 4 2021) |
| 22 June 2021 Buxton vs. Barnsley B (home: Midweek Mixed Div 4 2021) |
| 24 June 2021 Hallamshire D vs. Buxton (away: Ladies' Division 3 2021) |
| 29 June 2021 Buxton vs. Brentwood B (home: Midweek Mixed Div 4 2021) |
| 06 July 2021 Buxton vs Hallam Grange (home) |
